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bp0089 rrid ab 1107769  (Bio X Cell)


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    Bio X Cell bp0089 rrid ab 1107769
    Bp0089 Rrid Ab 1107769, supplied by Bio X Cell, used in various techniques. Bioz Stars score: 96/100, based on 298 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/bp0089+rrid+ab+1107769/InVivoPlus+rat+IgG2a+isotype+control%2C+anti-trinitrophenol/pmc13006444-23-10-7
    Average 96 stars, based on 298 article reviews
    bp0089 rrid ab 1107769 - by Bioz Stars, 2026-09
    96/100 stars

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    Figure 3. CD137 promotes Tex cell expansion and differentiation (A–D) Naive WT mice were treated with anti-CD137 (3H3, 10 mg) or <t>IgG</t> control mAbs. (A) Experimental design. (B–D) FACS plot and graphs showing Ki-67 expression by the indicated CD8+ T cell subsets along treatment.
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    Figure 3. CD137 promotes Tex cell expansion and differentiation (A–D) Naive WT mice were treated with anti-CD137 (3H3, 10 mg) or <t>IgG</t> control mAbs. (A) Experimental design. (B–D) FACS plot and graphs showing Ki-67 expression by the indicated CD8+ T cell subsets along treatment.
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    Figure 3. CD137 promotes Tex cell expansion and differentiation (A–D) Naive WT mice were treated with anti-CD137 (3H3, 10 mg) or IgG control mAbs. (A) Experimental design. (B–D) FACS plot and graphs showing Ki-67 expression by the indicated CD8+ T cell subsets along treatment.

    Journal: Immunity

    Article Title: TCR-independent CD137 (4-1BB) signaling promotes CD8 + -exhausted T cell proliferation and terminal differentiation.

    doi: 10.1016/j.immuni.2023.06.007

    Figure Lengend Snippet: Figure 3. CD137 promotes Tex cell expansion and differentiation (A–D) Naive WT mice were treated with anti-CD137 (3H3, 10 mg) or IgG control mAbs. (A) Experimental design. (B–D) FACS plot and graphs showing Ki-67 expression by the indicated CD8+ T cell subsets along treatment.

    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Anti-mouse CD45.1- FITC (A20) BD Biosciences Cat#: 110706 RRID: AB_313495 Anti-mouse TCRb-Perc PCy5.5 (H57-597) BioLegend Cat#:109228 RRID: AB_1575173 Anti-mouse CD155 (PVR) PE (TX56) BioLegend Cat#:131508 RRID: AB_1279107 Anti-mouse TIGIT-PeCy7 (1G9) BioLegend Cat#:142108 RRID: AB_2565649 Anti-mouse TIGIT-APC (1G9) BioLegend Cat#: 142105; RRID: AB_10962572 Anti-mouse Eomes-efluor660 (DAN11MAC) Thermo Fisher Scientific Cat#:50-4875-80 RRID: AB_2574227 Anti-mouse Ki67-AF700 (SOLA15) Thermo Fisher Scientific Cat#:56-5698-92 RRID: AB_2637480 Anti-mouse Eomes-EF450 (DAN11MAC) Thermo Fisher Scientific Cat#:48-4875-82 RRID: AB_2574062 Anti-mouse IFNg BV421 (XMG1.2) BD Biosciences Cat#: 505830 RRID: AB_2563105 Anti-mouse CD226-BV421 (TX42.1) BioLegend Cat#:133615 RRID: AB_2715977 Anti-mouse TCRb-BV510 (H57-597) Biolegend Cat#:109233 RRID: AB_2562349 Anti-mouse TCRb-PercPCy5.5 (H57-597) BioLegend Cat#:109228 RRID: AB_1575173 Anti-mouse CD62L-APC (MEL-14) invitrogen Cat#: 17-0621-81 RRID: AB_469410 Anti-mouse PD1 (CD279)-BV785 (29F.1A12) BioLegend Cat#:135225 RRID: AB_2563680 Anti-mouse PD-1 Bio X Cell Cat#: BP0146 RRID: AB_10949053 Anti-mouse OX40 Bio X Cell Cat#: BE0031 RRID: AB_1107592 Anti-mouse 4-1BB (CD137, 3H3) Bio X Cell Cat#: BE0239 RRID: AB_2687721 Anti-mouse 4-1BB (CD137, LOB12.3) Bio X Cell Cat#: BE0239 RRID: AB_10949016 Anti-mouse GITR Bio X Cell Cat#: BE0063 RRID: AB_1107688 Rat IgG2a Bio X Cell Cat#: BP0089 RRID: AB_1107769 Rat IgG1 Bio X Cell Cat#: BP0169 RRID: AB_1107775 Chemicals, peptides, and recombinant proteins Recombinant murine IL-7 Peprotech Cat#: 217-17 Brefeldin A Solution (1000X) Thermo Fisher Scientific Cat#: 00-4506-51 Golgi Plug BD Biosciences Cat#: 555029 Protein Transport Inhibitor BD Biosciences Cat#: 554724 Ionomycin Sigma-Aldrich Cat#: I0634 Phorboll 12-myristate 13-acetate (PMA) Sigma-Aldrich Cat#: P8139 RPMI Medium 1640 Thermo Fisher Scientific Cat#: 61870-010 Fetal Bovine Serum N/A N/A Ficoll Paque Plus Sigma-Aldrich Cat#: 17-1440-03 Acridine Orange / Propidium Iodide (AO/PI) Logos Biosystems Cat#: F23001 (Continued on next page) e2 Immunity 56, 1631–1648.e1–e10, July 11, 2023

    Techniques: Control, Expressing

    Figure 5. T cell-intrinsic CD137-induced canonical NF-kB signaling drives T cell exhaustion (A–D) Cd4creCd137fl/flROSA26tomato (tomato+) and Cd137fl/flROSA26tomato (tomato) mixed BM chimeras were treated with anti-CD137 (10 mg; 3H3, i.p. twice a week) or IgG control mAbs. (A) Experimental design. (B) Ratio of tomato and tomato+ among splenic CD8+ T cells. (C) Frequency and absolute number of CD8+

    Journal: Immunity

    Article Title: TCR-independent CD137 (4-1BB) signaling promotes CD8 + -exhausted T cell proliferation and terminal differentiation.

    doi: 10.1016/j.immuni.2023.06.007

    Figure Lengend Snippet: Figure 5. T cell-intrinsic CD137-induced canonical NF-kB signaling drives T cell exhaustion (A–D) Cd4creCd137fl/flROSA26tomato (tomato+) and Cd137fl/flROSA26tomato (tomato) mixed BM chimeras were treated with anti-CD137 (10 mg; 3H3, i.p. twice a week) or IgG control mAbs. (A) Experimental design. (B) Ratio of tomato and tomato+ among splenic CD8+ T cells. (C) Frequency and absolute number of CD8+

    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Anti-mouse CD45.1- FITC (A20) BD Biosciences Cat#: 110706 RRID: AB_313495 Anti-mouse TCRb-Perc PCy5.5 (H57-597) BioLegend Cat#:109228 RRID: AB_1575173 Anti-mouse CD155 (PVR) PE (TX56) BioLegend Cat#:131508 RRID: AB_1279107 Anti-mouse TIGIT-PeCy7 (1G9) BioLegend Cat#:142108 RRID: AB_2565649 Anti-mouse TIGIT-APC (1G9) BioLegend Cat#: 142105; RRID: AB_10962572 Anti-mouse Eomes-efluor660 (DAN11MAC) Thermo Fisher Scientific Cat#:50-4875-80 RRID: AB_2574227 Anti-mouse Ki67-AF700 (SOLA15) Thermo Fisher Scientific Cat#:56-5698-92 RRID: AB_2637480 Anti-mouse Eomes-EF450 (DAN11MAC) Thermo Fisher Scientific Cat#:48-4875-82 RRID: AB_2574062 Anti-mouse IFNg BV421 (XMG1.2) BD Biosciences Cat#: 505830 RRID: AB_2563105 Anti-mouse CD226-BV421 (TX42.1) BioLegend Cat#:133615 RRID: AB_2715977 Anti-mouse TCRb-BV510 (H57-597) Biolegend Cat#:109233 RRID: AB_2562349 Anti-mouse TCRb-PercPCy5.5 (H57-597) BioLegend Cat#:109228 RRID: AB_1575173 Anti-mouse CD62L-APC (MEL-14) invitrogen Cat#: 17-0621-81 RRID: AB_469410 Anti-mouse PD1 (CD279)-BV785 (29F.1A12) BioLegend Cat#:135225 RRID: AB_2563680 Anti-mouse PD-1 Bio X Cell Cat#: BP0146 RRID: AB_10949053 Anti-mouse OX40 Bio X Cell Cat#: BE0031 RRID: AB_1107592 Anti-mouse 4-1BB (CD137, 3H3) Bio X Cell Cat#: BE0239 RRID: AB_2687721 Anti-mouse 4-1BB (CD137, LOB12.3) Bio X Cell Cat#: BE0239 RRID: AB_10949016 Anti-mouse GITR Bio X Cell Cat#: BE0063 RRID: AB_1107688 Rat IgG2a Bio X Cell Cat#: BP0089 RRID: AB_1107769 Rat IgG1 Bio X Cell Cat#: BP0169 RRID: AB_1107775 Chemicals, peptides, and recombinant proteins Recombinant murine IL-7 Peprotech Cat#: 217-17 Brefeldin A Solution (1000X) Thermo Fisher Scientific Cat#: 00-4506-51 Golgi Plug BD Biosciences Cat#: 555029 Protein Transport Inhibitor BD Biosciences Cat#: 554724 Ionomycin Sigma-Aldrich Cat#: I0634 Phorboll 12-myristate 13-acetate (PMA) Sigma-Aldrich Cat#: P8139 RPMI Medium 1640 Thermo Fisher Scientific Cat#: 61870-010 Fetal Bovine Serum N/A N/A Ficoll Paque Plus Sigma-Aldrich Cat#: 17-1440-03 Acridine Orange / Propidium Iodide (AO/PI) Logos Biosystems Cat#: F23001 (Continued on next page) e2 Immunity 56, 1631–1648.e1–e10, July 11, 2023

    Techniques: Control